Bone Cancer (Osteosarcoma) is the most common primary malignant bone tumour, excluding myeloma and lymphoma. There is a predilection for the metaphyseal region of tubular long bones. 50% of cases occur around the knee. Bone Cancer (osteogenic sarcoma) is a malignant connective (soft) tissue tumor whose neoplastic cells present osteoblastic differentiation and form tumoral bone.
In children, 5% of all cancers are seen as bone cancer. 75% of all cases occur in patients below the age of 20. Looking at the distribution of cases by age from here, a second peak in incidence occurs in the elderly, usually associated with an underlying bone pathology such as Paget’s disease, medullary infarct, or prior irradiation.
In all cases, the tumor may be localized at the metaphyseal end of the long bones. Most often it affects the upper end of tibia or humerus, of lower end of femurus. The tumor is solid, hard, irregular […]
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